Serum angiotensin converting enzyme activity in sarcoidosis and pulmonary tuberculosis.

Serum angiotensin converting enzyme (SACE) was estimated in 18 cases of sarcoidosis, 15 patients suffering from pulmonary tuberculosis and in 12 normal healthy individuals. SACE was elevated in the patients suffering from sarcoidosis. (33.2 +/- 12.9). SACE values for the pulmonary tuberculosis patients were 18.8 +/- 7.9 and those for the normal healthy individuals were 17.1 +/- 4.7. Compared to pulmonary tuberculosis and normal healthy individuals, the SACE levels were significantly elevated (P < 0.01) in sarcoidosis patients.

HLA association with sarcoidosis and diffuse interstitial pulmonary fibrosis.

HLA typing was performed on 18 patients suffering from sarcoidosis and 30 patients suffering from diffuse interstitial pulmonary fibrosis. One hundred normal healthy people ethnically matched served as the controls. On statistical analysis, the corrected 'p' value of all the HLA antigens for both the patient groups was non significant. The results therefore suggest that there is no particular HLA antigen associated with sarcoidosis and diffuse interstitial pulmonary fibrosis.